Botanical Breast Enhancement: Guide

Biology

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Breast development

The hormones of estrogens, progestogens, prolactin and androgens influence breast tissue through Estrogen Receptor Alpha (ERα), Progesterone Receptor B (PRB) and Prolactin Receptor (PrlR). ERα, Estrogen Receptor Beta (ERβ) and progesterone receptors (PR) in the reproductive tract are important for estrogen balance and fertility. As each receptor is positively stimulated by its respective hormone, it also becomes desensitized. There are more receptor types in the breast and body that cannot be ignored due to health reasons.

Positive estrogenic stimulation, or agonism, of ERα causes lengthening of milk ducts. Branching of milk ducts, which increases the amount of end buds, is caused by progestogenic agonism on PRB. The formation of milk lobules converted from the end of milk ducts and their continued growth is caused by prolactin’s effects on PrlR. Progesterone also has a role in differentiation, or conversion of end points into milk lobules, by influencing prolactin, during secretory phase.

Endocrinology

Of ERα, ERβ and PRB, mild potentencies of their non-respective steroid hormone enhances each hormone receptor’s response to its respective hormone, known as receptor upregulation. Without compatible synergistic action, the response to a receptor’s own specific hormone dulls with quantity or potency, known as receptor downregulation. Upregulation and downregulation also applies to non-steroid hormone receptors like PrlR. Too much of a potent hormone can damage its own and other interacting receptors. An imbalance of too much of one type of hormone is a cancer and fertility risk. The breast and reproductive tract contain more types of cell receptors, but the mentioned above are the focus so far.

Estrogens are formed from androgens through a process called aromatase, and aromatase enzymes are located within tissue where ERα and ERβ are also present. ERβ is located in ovarian, egg, bone, brain and adipose tissue. Within the ovarian follicle or corpus luteum, androgen production by theca cells, and estrogen production by granulosa cells are together important for reproductive health.

Estrogens, progestogens, androgens, glucocorticoids and mineralocorticoids are steroid hormones which are fat soluble. Steroid hormones react with their respective receptors within cells.

Follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (Prl), anti-müllerian hormone (AMH) and inhibin are amino acid based hormones that regulate the menstrual cycle. These hormones do not last as long in the body as steroid hormones, and these hormones interact with receptors at cells walls. Balance of these non-steroid hormones, and the health of their corresponding receptors is also important.

Menstrual cycle

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The menstrual cycle will be divided into the following 4 phases to simplify timing: menses (menstruation), proliferative, secretory and premenstrual. Follicular phase has been divided up into menses and proliferative phases. Menstruation is when the uterus lining is shed. The proliferative phase is when the uterus rebuilds to prepare for potential pregnancy, and this lasts from the end of menstruation until ovulation. Ovulation is an intermediate time between proliferative and secretory phases. The luteal phase has been divided into secretory and premenstrual phases. The corpus luteum, which produces progesterone, is present during the secretory phase. Premenstrual phase begins after the corpus luteum disintegrates, and it lasts until menstruation starts.

During menstruation, FSH increases menstruation intensity, and prolactin decreases menstruation intensity. Estrogen is not a dominant hormone during menstruation. FSH develops the follicle, but it also causes follicles to be released.

During proliferative phase, one or few follicles continue to develop which raises inhibin and estrogen. Inhibin signals the pituitary to not release FSH, and for new follicles not to be released. Rising estrogen levels prepare the reproductive tract for egg implantation. Estrogen suppresses LH at first, but a buildup of estrogen eventually causes the body to release LH.

LH allows ovulation to occur, releasing the egg from the follicle, leaving behind the corpus luteum in the ovary. The sequential rise of LH, then FSH initially matures the corpus luteum within the ovary during ovulation. FSH then pushes the egg towards the uterus.

Progesterone is produced by the corpus luteum, which is a temporary organ whose function is to signal to the pituitary gland to momentarily prevent menstruation, for purposes of maintaining fertilization or pregnancy. Lower amounts of estrogens than progestogens are produced during the luteal phase and pregnancy. The pituitary gland releases prolactin, which signals the corpus luteum (and if during pregnancy, the placenta) to release more progesterone, creating a feedback loop. Progesterone increases prolactin, and prolactin lowers FSH and LH.

If the egg is not fertilized, the corpus luteum dies within the ovaries. Once progesterone levels drop during premenstrual phase, the pituitary gland begins to release FSH, allowing menstruation to begin. Outside of the secretory phase, early premenstrual phase or pregnancy, progesterone amounts in the body are existent (due to the adrenal glands), but negligible.

About

This is from chapter 1 from breast-endocrinology.pdf. The next chapter is Hormone Imbalances. super-bazongas.pdf continues on herb use.

Images are not included in permissive license of these ebooks.


Breast enhancement; health blog

- October 12, 2021
Limit fat soluble vitamins

- September 08, 2021
Still doing work on NBE

About swelling - June 30, 2021
Hints for swelling

About plateauing - May 24, 2021
Hint for plateauing

Anon08 - May 31, 2021
New picture of growth

Menses phase update - May 24, 2021
Update for herb schedule for menses

Estrogenic properties of hops and thistles - May 05, 2021
Hops has phytoestrogens that circulate continuously in the body. Anecdotally, thistles seems to behave like this towards different estrogen receptors.

Supplement efficacy - April 28, 2021
In one program, the effects of a supplement didn't work completely as expected. This was compensated for.

Herb schedule update - April 28, 2021
Herb schedule was improved and works more consistently for proliferative phase, secretory phase and with BCP use.

Updated theory on progesterone response for herb schedule - April 17, 2021
Focus primarily on progesterone response, then secondarily on estrogen response for proliferative and luteal phases. Aim for breast widening and hip growth, rather than breast elongation.

Progesterone balance - April 15, 2021
Progesterone balance

Hirsutism04 - April 12, 2021
Hirsutism04 program

Anon08: consistent growth - March 14, 2021
Consistent growth of about a cup size per month.

Herbs with primarily phytoprogestin properties - April 27, 2021
Herbs and edible oils that contain phytoprogestins and aren't noticeably estrogenic.

Herbs similar to fenugreek - February 11, 2021
Herbs that are similar to fenugreek: that they contain both phyto-progestins and phyto-estrogens. These herbs may contain different balances of these phytohormones and contain other varying properties.

NBE guide - February 10, 2021
Basic guide and updated herb schedules for botanical breast enlargement. Also, an ideal starting point.

Luteal phase program - February 02, 2021
Herb program for luteal phase, and parts of documented herb program showing minor growth.

About BCP use - February 02, 2021
About birth control pill (BCP) use and cycles. Another program is documented here showing growth.

Adjustment of sesame use - January 26, 2021
Adjustments to proportion of sesame seed.

Topical use - January 25, 2021
Avoid using topicals on hip area, so hormonal effects on the surface can be expected to be the same as on the reproductive tract. Also, limit topicals to secretory phase, complementary to the herb schedule.

Maca; Lepidium meyenii - February 05, 2021
Basic hormonal and beneficial metabolic properties.

Hirsutism02 journal - March 29, 2020
Improvement of alcopecia and hirsutism. Her hair conditions improved: body hair lowered, and scalp hair has grown back. There were noticeable but minor gains in breast and hip size.

Jellies's NBE results - April 05, 2020
Before and after of Jellie's breast growth, from about 1 month on a herb program. Latest picture is of February 10, 2020. She also had described hip growth, that is not shown in pictures. [Results are from a C cup to an E cup.]

Breast Development and Endocrinology, 3rd Ed - May 22, 2019
Expanded and clarified details for Breast Development and Endocrinology 3rd edition. From now on, this will be volume 1. These edits will reflect in Super Bazongas. Herb schedule will be edited, but same herb combinations will be used as basis. Future releases of Super Bazongas will be volume 2.

Super Bazongas, volume 2; note - February 11, 2021
Super Bazongas, Vol 2, is currently unavailable. It will be updated at a later time. See program journals for more recent information. See the guide, especially

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